“Informational accounting will reveal that any improvements in replicase function in ribozymes are the result of active informa¬tion supplied by ribozyme engineers.”
This is the experimental biochemistry version of the computer simulation prediction (see #2). Meyer discusses in some degree of detail how origin-of-life researchers strive to demonstrate experimentally how replicase functions can arise from various RNA-world molecules such as ribozymes. His complaint is that any progress claimed to demonstrate development of new function is actually the result of information actively supplied by the biochemists setting up the experiment.
The challenge seems to be a natural extension of the basic claim Meyer is making, namely that all complex specified information is the result of the action of an intelligent agent. Yet, the challenge may be a catch-22. Experimental verification of even a small part of an evolutionary process requires researchers to set up the environment in such a way as to obtain results in about eight orders of magnitude faster time than might have happened in evolution. This necessarily involves some artificial influence of the starting points or the environmental conditions. The rules of informational accounting are sufficiently vague that separating the active information required to set up the experiment from active information unfairly generating the target information is to some degree in the eye of the beholder. Once again, the prediction might be met but few will change their mind about ID as a result.